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PHASE 2 RESULTS: This is a phase 2, 13-week randomized, double-blind, placebo-controlled, parallel arm study that will evaluate the safety, tolerability, weight loss efficacy of NA-931 in adults who are obese (BMI 30 kg/m2) or who are overweight (BMI 27 kg/m2) with at least one weight-related co-morbid condition
Neurotoxic reactive astrocytes are induced by activated microglia
Unlike semaglutide (Wegovy), which targets only the GLP-1 receptor, or tirzepatide (Zepbound), which targets GLP-1 and GIP receptors, retatrutide activates three receptors simultaneously: GLP-1, GIP, and glucagon
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